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April Webinar: Canine on the Couch: The New Canary in the Coal Mine for Environmental Health Studies
April 26, 2022 @ 1:00 pm - 2:00 pm
The environment undoubtedly influences human health, yet the extent of its impact remains a significant challenge to address. The long latency period associated with the development of chronic human diseases (e.g. cancer, heart disease) is a major obstacle to identifying potential links to environmental exposures that occur early in life. To better understand risks to population health from environmental exposures we need more research to accurately and reliably assess environmental exposures throughout the lifetime. Our dogs spend their whole lives sharing our environment and many of our daily exposures to pollutants. Moreover, the canine and human genomes are closely related and the One Health concept has shown that both species develop diseases, including cancers, with shared clinical and biological features. With a 6-8 fold shorter lifespan than most humans, use of pet dogs as a sentinel species can help elucidate links between chemical exposures and related human disease. To support this research direction, we conducted a study to investigate chemical exposures among pet dogs and their paired human companions using silicone dog-tags and wristbands. This presentation will discuss the use of silicone passive sampling devices in pet dogs and demonstrate that pet dogs can act as surrogates for human exposures in the home environment, potentially providing a new way to study relationships between environmental exposures and disease etiology.
Presenter: Dr. Catherine Wise, Duke University